THE HIV INSTITUTE ROYAL ORGANIZATION

Instroduction:

The Hiv Royal Institue Organization is a group, devote to study and develope Hiv. we offer some technique information and some latest new in this field. At the same time we offer the contact plat for Medicine and drug doctor

Integration of Viral DNA

Once the viral RNA has been reverse-transcribed into a strand of DNA, the DNA can then be integrated (inserted) into the DNA of the lymphocyte. The virus has its own enzyme called "integrase" that facilitates incorporation of the viral DNA into the host cells DNA. The integrated DNA is called a provirus Transcription: Back to RNA As long as the lymphocyte is not activated or "turned-on", nothing happens to the viral DNA.But if the lymphocyte is activated, transcription of the viral DNA begins, resulting in the production of multiple copies of viral RNA. This RNA codes for the production of the viral proteins and nzymes (translation) and will also be packaged later as new viruses.

Translation: RNA -> Proteins

There are only 9 genes in the HIV RNA. Those genes have the code necessary to produce structural proteins such as the viral envelope and core plus enzymes like reverse transcriptase, integrase, and a crucial enzyme called a protease. Integration of Viral DNA Once the viral RNA has been reverse-transcribed into a strand of DNA, the DNA can then be integrated (inserted) into the DNA of the lymphocyte. The virus has its own enzyme called "integrase" that facilitates incorporation of the viral DNA into the host cells DNA. The integrated DNA is called a provirus.

Translation: RNA -> Proteins

There are only 9 genes in the HIV RNA. Those genes have the code necessary to produce structural proteins such as the viral envelope and core plus enzymes like reverse transcriptase, integrase, and a crucial enzyme called a protease.